2020
Morozumi A., Kamiya M., Uno S., Umezawa K., Kojima R., Yoshihara T., Tobita S., Urano Y. (2020) Spontaneously blinking fluorophores based on nucleophilic addition/dissociation of intracellular glutathione for live-cell super-resolution imaging. J. Am. Chem. Soc., 142 (21): 9625–9633.
doi: 10.1021/jacs.0c00451.
Rivas C., Kamiya M., Urano Y. (2020) A novel sialidase-activatable fluorescence probe with improved stability for the sensitive detection of sialidase. Bioorg. Med. Chem. Lett., 30: 126860.
doi: 10.1016/j.bmcl.2019.126860.
2019
Yamamoto K., Kamiya M., Urano Y. (2019) Highly sensitive fluorescence imaging of cancer with avidin-protease probe conjugate. Bioorg. Med. Chem. Lett., 9: 126663.
doi: 10.1016/j.bmcl.2019.126663.
Kawatani M., Yamamoto K., Yamada D., Kamiya M., Miyakawa J., Miyama Y., Kojima R., Morikawa T., Kume H., Urano Y. (2019) Fluorescence Detection of Prostate Cancer by an Activatable Fluorescence Probe for PSMA Carboxypeptidase Activity. J. Am. Chem. Soc. 14, 10409-10416.
doi: 10.1021/jacs.9b04412.
Ogasawara A., Kamiya M., Sakamoto K., Kuriki Y., Fujita K., Komatsu T., Ueno T., Hanaoka K., Onoyama H., Abe H., Tsuji Y., Fujishiro M., Koike K., Fukayama M., Seto Y., Urano Y. (2019) Red Fluorescence Probe Targeted to Dipeptidylpeptidase-IV for Highly Sensitive Detection of Esophageal Cancer. Bioconjug. Chem., 30(4): 1055-1060.
doi: 10.1021/acs.bioconjchem.9b00198.
2018
Uno S., Kamiya M., Morozumi A., Urano Y. (2018) A green-light-emitting, spontaneously blinking fluorophore based on intramolecular spirocyclization for dual-colour super-resolution imaging. Chem. Comm., 54: 102-105.
doi: 10.1039/c7cc07783a.
Ito H., Kawamata Y., Kamiya M., Tsuda-Sakurai K., Tanaka S., Ueno T., Komatsu T., Hanaoka K., Okabe S., Miura M., Urano Y. (2018) Red-shifted fluorogenic substrate for detecting lacZ‐positive cells in living tissue with single-cell resolution. Angew. Chem. Int. Ed. 57(48):15702-15706.
doi: 10.1002/anie.201808670.
Umezawa K., Kamiya M., Urano Y. (2018) A reversible fluorescent probe for real-time live-cell imaging and quantification of endogenous hydropolysulfides. Angew. Chem. Int. Ed. 57(30): 9346-9350.
doi:10.1002/anie.201804309.
Kuriki Y., Kamiya M., Kubo H., Komatsu T., Ueno T., Tachibana R., Hayashi K., Hanaoka K., Yamashita S., Ishizawa T., Kokudo N., Urano Y. (2018) Establishment of Molecular Design Strategy To Obtain Activatable Fluorescent Probes for Carboxypeptidases. J. Am. Chem. Soc., 140(5): 1767-1773.
doi:10.1021/jacs.7b11014.
Iwatate R.J., Kamiya M., Umezawa K., Kashima H., Nakadate M., Kojima R., Urano Y. (2018) Silicon Rhodamine-Based Near-Infrared Fluorescent Probe for γ-Glutamyltransferase. Bioconjug Chem., 29(2): 241-244.
doi:10.1021/acs.bioconjchem.7b00776.
Kawatani M., Kamiya M., Takahashi H., Urano Y. (2018) Factors affecting the uncaging efficiency of 500nm light-activatable BODIPY caging group. Bioorganic & Medicinal Chemistry Letters, 28(1):1-5.
doi:10.1016/j.bmcl.2017.11.030.
2017
Uno S., Kamiya M., Morozumi A., Urano Y. (2017) A green-light-emitting, spontaneously blinking fluorophore based on intramolecular spirocyclization for dual-colour super-resolution imaging. Chemical Communications, 54(1): 102-105.
doi:10.1039/c7cc07783a.
Chiba M., Ichikawa Y., Kamiya M., Komatsu T., Ueno T., Hanaoka K., Nagano T., Lange N., Urano Y. (2017) An Activatable Photosensitizer Targeted to γ-Glutamyltranspeptidase. Angew. Chem. Int Ed. Engl., 56(35): 10418-10422.
doi:10.1002/anie.201704793.
Yogo T., Umezawa K., Kamiya M., Hino R., Urano Y. (2017) Development of an Activatable Fluorescent Probe for Prostate Cancer Imaging. Bioconjug Chem., 28(8): 2069-2076.
doi:10.1021/acs.bioconjchem.7b00233.
Takakura H., Zhang Y., Erdmann S.R., Thompson D.A., Lin Y., McNellis B., Rivera-Molina F., Uno S., *Kamiya M., Urano Y., Rothman E.J., Bewersdorf J., Schepartz A., Toomre D. (2017) Long time-lapse nanoscopy with spontaneously blinking membrane probes. Nature Biotechnology, 35(8): 773-780.
doi:10.1038/nbt.3876.
Umezawa K., Yoshida M., Kamiya M., Yamasoba T., Urano Y. (2017) Rational design of reversible fluorescent probes for live-cell imaging and quantification of fast glutathione dynamics. Nature Chemistry, 9(3): 279-286.
doi:10.1038/nchem.2648.
2016
Iwatate R.J., Kamiya M., Urano Y. (2016) Asymmetric Rhodamine-Based Fluorescence Probes for Multi-colour In Vivo Imaging. Chem-Eur. J., 22: 1696-1703.
doi: 10.1002/chem.201503426.
Doura T., Kamiya M., Obata F., Yamaguchi Y., Hiyama T.Y., Matsuda T., Fukamizu A., Noda M., Miura M., Urano Y. (2016) Detection of LacZ-Positive Cells in Living Tissue with Single-Cell Resolution. Angew. Chem. Int. Ed., 55: 9620-9624.
doi: 10.1002/anie.201603328.
Hino H., Kamiya M., Kitano K., Mizuno K., Tanaka S., Nishiyama N., Kataoka K., Urano Y., Nakajima J. (2016) Rapid Cancer Fluorescence Imaging Using A γ-Glutamyltranspeptidase-Specific Probe For Primary Lung Cancer. Transl. Oncol., 9: 203-210.
doi: 10.1016/j.tranon.2016.03.007.
Onoyama H., Kamiya M., Kuriki Y., Komatsu T., Abe H., Tsuji Y., Yagi K., Yamagata Y., Aikou S., Nishida M., Mori K., Yamashita H., Fujishiro M., Nomura S., Shimizu N., Fukayama M., Koike K., Urano Y., Seto Y. (2016) Rapid and sensitive detection of early esophageal squamous cell carcinoma with fluorescence probe targeting dipeptidylpeptidase IV. Sci., Rep. 6: 26399.
doi: 10.1038/srep26399.
Kamiya M., Urano Y. (2016) Rapid and sensitive fluorescent imaging of tiny tumors in vivo and in clinical specimens. Curr. Opin. Chem. Biol., 33: 9-15.
doi: 10.1016/j.cbpa.2016.04.004.
Matsuzaki H., Kamiya M., Iwatate R.J., Asanuma D., Watanabe T., Urano Y. (2016) Novel Hexosaminidase-Targeting Fluorescence Probe for Visualizing Human Colorectal Cancer. Bioconjug. Chem., 27: 973-981.
doi: 10.1021/acs.bioconjchem.6b00037.
Iwatate R.J., Kamiya M., Urano Y. (2016) Asymmetric Rhodamine-Based Fluorescent Probe for Multicolour In Vivo Imaging. Chemistry, 22: 1696-1703.
doi: 10.1002/chem.201503426.
2015
Kojima R., Takakura H., Kamiya M., Kobayashi E., Komatsu T., Ueno T., Terai T., Hanaoka K., Nagano T., Urano Y. (2015) Development of a Sensitive Bioluminogenic Probe for Imaging Highly Reactive Oxygen Species in Living Rats. Angew. Chem. Int. Ed., 54: 14768-14771.
doi: 10.1002/anie.201507530.
Uno S.N., Tiwari D.K., Kamiya M., Arai Y., Nagai T., Urano Y. (2015) A guide to use photocontrollable fluorescent proteins and synthetic smart fluorophores for nanoscopy. Microscopy, 64: 263-277.
doi: 10.1093/jmicro/dfv037.
