The aim of this study is to develop a chemical tag system that allows genetically targeted fluorescence imaging in living organisms using near-infrared fluorescence at wavelengths higher than 800 nm. As an empirical application, we will perform whole-body imaging of cancer metastasis in mice and demonstrate the usefulness of the proposed system.
2020
Kitajima N., Takikawa K., Sekiya H., Satoh K., Asanuma D., Sakamoto H., Takahashi S., Hanaoka K., Urano Y., Namiki S., Iino M., Hirose K. (2020) Real-time in vivo imaging of extracellular ATP in the brain with a hybrid-type fluorescent sensor. eLife, 9:e57544.
doi: 10.7554/eLife.57544.
2018
Sakamoto H., Ariyoshi T., Kimpara N., Sugao K., Taiko I., Takikawa K., Asanuma D., Namiki S. Hirose K. (2018) Synaptic weight set by Munc13-1 supramolecular assemblies. Nat. Neurosci., 21, 41-49.
doi:10.1038/s41593-017-0041-9.
