RESEARCH CONCEPT

RESONANT INTERACTIONS BETWEEN LIGHT AND BIOMOLECULES

CONTENT OF RESEARCH PROJECTS

Given the project’s liberal environment, all the members will have a chance to share several critical problems confronting current bioimaging. Although subject to change, examples include “What are the forthcoming techniques for super-resolution and deep imaging?”, “How should we investigate stress, an ambiguous phenomenon, both intensively and extensively?”, “How can we zoom in on and out of a biological structure at diverse spatial scales?”, “How should we cope with terabyte image data?”, and “What are the theoretical and practical dimensions of bioimaging?”.

While this project focuses on the interaction between light and molecules, it may also incorporate technologies from other areas, such as those that employ electrons and sound. In addition, non-life scientists are highly welcome.For example, software contests sponsored by this project are expected to motivate general programmers to take the plunge into bioimaging. We will actively disseminate information on the progress and achievements of this project worldwide through our publications and the Web.

Our efforts will hopefully speed up the progress of many life sciences in Japan as we address the growing needs of those fields.

A01 Molecular Design

Large-scale, high-resolution in vivo imaging
Live imaging of intercellular communication
Deeper and Precise Fluorescence Bioimaging through the Second Biological Window (SBW)
Development of fluorescence imaging probes based on new mechanism of fluorescence switching.

A02 Light Control

Cancer metastasis research that makes full use of innovative imaging technology and medaka as a model of cancer
Improvement and applications of fast in vivo imaging using vector beams
BioImage Processing

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